Brain SPECT in dementia a clinical-scintigraphic correlation

Arquivos de Neuro-Psiquiatria

Carlos A. Buchpiguel¹  Sandra C. Mathias²  Liliam Y. Itaya¹  Nélio G. Barros¹  Luis A.p. Portela²  Jose M. M. Freitas²  Paulo Caramelli²  Paulo E. Carrilho²  Luiz A. Bacheschi²  Fausto H Hironaka¹  Ricardo Nitrini² 

[1] ,São Paulo University School of Medicine Department of Neurology

关键词: SPECT;    computed tomography;    dementia;    Alzheimer's disease;    HMPAO-Tc99m;    SPECT;    tomografia computadorizada;    demência;    doença de Alzheimer;    HMPAO-Tc99m;   

DOI  :  10.1590/S0004-282X1996000300003

来源: SciELO

【 摘 要 】

The aim of this study was to compare the accuracy of computed tomography (CT) and single photon emission computerized tomography (SPECT) in the diagnosis of dementia. Fifty-two patients with clinical diagnosis of dementia and 11 controls were studied. The scans were interpreted by one experienced neuroradiologist and one nuclear radiologist, both blinded to the clinical data. In the diagnosis of dementia, CT and SPECT showed equal sensitivity (82.7%) and statistically similar specificity (63.8 and 81.8%, respectively). The specificity of SPECT in diagnosing Alzheimer's disease (100%) was statistically superior to CT (69%). However, both methods showed similar sensitivity in detecting Alzheimer's disease. In conclusion, SPECT and CT showed similar accuracy in the diagnosis of dementia. The quite high specificity of SPECT in Alzheimer's disease may be useful for confirming that diagnosis, particularly for patients with presenile onset of the disease.

【 授权许可】

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