Arquivos de Neuro-Psiquiatria | |
Brain SPECT in dementia a clinical-scintigraphic correlation | |
Carlos A. Buchpiguel1  Sandra C. Mathias2  Liliam Y. Itaya1  Nélio G. Barros1  Luis A.p. Portela2  Jose M. M. Freitas2  Paulo Caramelli2  Paulo E. Carrilho2  Luiz A. Bacheschi2  Fausto H Hironaka1  Ricardo Nitrini2  | |
[1] ,São Paulo University School of Medicine Department of Neurology | |
关键词: SPECT; computed tomography; dementia; Alzheimer's disease; HMPAO-Tc99m; SPECT; tomografia computadorizada; demência; doença de Alzheimer; HMPAO-Tc99m; | |
DOI : 10.1590/S0004-282X1996000300003 | |
来源: SciELO | |
【 摘 要 】
The aim of this study was to compare the accuracy of computed tomography (CT) and single photon emission computerized tomography (SPECT) in the diagnosis of dementia. Fifty-two patients with clinical diagnosis of dementia and 11 controls were studied. The scans were interpreted by one experienced neuroradiologist and one nuclear radiologist, both blinded to the clinical data. In the diagnosis of dementia, CT and SPECT showed equal sensitivity (82.7%) and statistically similar specificity (63.8 and 81.8%, respectively). The specificity of SPECT in diagnosing Alzheimer's disease (100%) was statistically superior to CT (69%). However, both methods showed similar sensitivity in detecting Alzheimer's disease. In conclusion, SPECT and CT showed similar accuracy in the diagnosis of dementia. The quite high specificity of SPECT in Alzheimer's disease may be useful for confirming that diagnosis, particularly for patients with presenile onset of the disease.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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