Literature systematic review on the ophthalmological side effects of interferons

Arquivos Brasileiros de Oftalmologia

Yara Dadalti Fragoso²  Marina Sanchez Sahm Paggiaro¹  Roberta Mastromauro¹  Gabriela Da Silva Jacondino¹  Heather Marion Wilson¹ 

[1] ,Universidade Metropolitana de Santos Department of Neurology Santos SP ,Brazil

关键词: Eye;    Retina;    Interferon alpha;    Interferon beta;    Olho;    Retina;    Interferon alfa;    Interferon beta;   

DOI  :  10.1590/S0004-27492011000400017

来源: SciELO

【 摘 要 】

Interferons alpha and beta have been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complications of interferon therapy have been published. The objective of this study was to carry out a literature systematic review on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment. Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhages and retina ischemia.

【 授权许可】

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