Annellation of Triazole and Tetrazole Systems onto Pyrrolo[2,3-d]pyrimidines: Synthesis of Tetrazolo[1,5-c]-pyrrolo[3,2-e]-pyrimidines and Triazolo[1,5-c]pyrrolo-[3,2-e]pyrimidines as Potential Antibacterial Agents

Molecules

Chaitanya G. Dave¹ 

[1] Organic Syntheses Laboratory, M.G. Science Institute, Navrangpura, Ahmedabad 380 009, India

关键词: Tetrazolopyrrolopyrimidines;    triazolopyrrolopyrimidines;    pyrrolo[2;    3-d]- pyrimidines;    antibacterial activity;   

DOI  :  10.3390/70700554

来源: mdpi

【 摘 要 】

Syntheses of several novel 4-chloropyrrolo[2,3-d]pyrimidines (1), 4-hydrazinopyrrolo[2,3-d]pyrimidines (2) and 3-amino-4-iminopyrrolo[2,3-d]pyrimidines (7) and their use in the synthesis of tetrazolo[1,5-c]pyrrolo[3,2-e]pyrimidines (3) and triazolo[1,5-c]pyrrolo[3,2-e]pyrimidines (4) required for biological screening are reported.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.