6-(4-Amino-1-methyl-2-(methylthio)-6-oxo-1,6-dihydro-pyrimidin-5-yl)-3,6-dimethyl-2-(methylthio)-6,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-4,5-dione

Molbank

Pablo E. Romo¹  Jairo Quiroga¹  Braulio Insuasty¹  Manuel Nogueras¹ 

[1] ¹Heterocyclic Compound Research Group, Department of Chemistry, Universidad del Valle,A.A. 25360 Cali, Colombia ²Department of Inorganic and Organic Chemistry, Universidad de Jaén, 23071 Jaén, Spain

关键词: pyrrolo[2;    3-d]pyrimidine;    microwave irradiation;    cerium ammonium nitrate;   

DOI  :  10.3390/M842

来源: mdpi

【 摘 要 】

The title compound 6-(4-amino-1-methyl-2-(methylthio)-6-oxo-1,6-dihydro-pyrimidin-5-yl)-3,6-dimethyl-2-(methylthio)-6,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-4,5- dione was synthesized in 60% yield by a microwave-induced cyclocondensation reaction of aminopyrimidine with pyruvic acid in the presence of cerium ammonium nitrate (CAN)as catalyst.

【 授权许可】

CC BY   
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