Reagents for Lithium Electrodes and Sensors for Blood Serum Analysis

Sensors

关键词: Spectrophotometry;    Fluorescence;    Sensors;    Ion-Selective Electrodes;    Crown Ethers;    Cryptands;    Diamide Ionophores;   

DOI  :  10.3390/s21000432

来源: mdpi

【 摘 要 】

The measurement of lithium in blood serum requires high selectivity since the blood contains about 140 mM sodium compared to the 0.5-1.5 mM lithium level in manic depressive patients under treatment with lithium salts. This review traces the development of optical and potentiometric methods for the selective measurement of lithium in the presence of sodium. Selectivities of over 1,000:1 are achievable with properly designed ionophores.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.