A Comparison of Microwave-Accelerated Conventionally Heated Iodination Reactions of Some Arenes Heteroarenes Using ortho-Periodic Acid as the Oxidant†

Molecules

Maciej Sosnowski¹ 

[1] Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, 1 Banacha Street, PL 02-097 Warsaw, Poland.

关键词: Oxidation;    ortho-periodic acid as oxidant;    oxidative iodination of activated arenes and heteroarenes;    diiodine;    microwave irradiation;   

DOI  :  10.3390/10020401

来源: mdpi

【 摘 要 】

A fast and simple method for the oxidative iodination of some activated arenes and heteroarenes, either under microwave irradiation or by conventional heating, is reported, using diiodine and ortho-periodic acid as the oxidant. The reactions were carried out in hot 95% ethanol under a reflux condenser. For the microwave assisted reactions, the reaction times were always notably shortened, but the yields were nearly the same as those afforded by the conventional method.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).