Efficient Ce(NO3)3·6H2O-Catalyzed Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones

Molecules

Mehdi Adib¹  Khadijeh Ghanbary²  Manizheh Mostofi² 

[1] id="af1-molecules-11-00649">School of Chemistry, University College of Science, University of Tehran, P. O. Box 14155-6455, Tehran, Ir

关键词: Dihydropyrimidinones;    cerium(III) nitrate;    Biginelli reaction;    solvent-free synthesis;   

DOI  :  10.3390/11080649

来源: mdpi

【 摘 要 】

Cerium(III) nitrate hexahydrate efficiently catalyzes the three-component Biginelli reaction under solvent-free conditions of an aldehyde, a β-keto ester or β-diketone and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or –thiones in excellent yields.

【 授权许可】

Unknown   
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