Synthesis of 4-Aryl Substituted 3,4-Dihydropyrimidinones Using Silica-chloride Under Solvent Free Conditions

Molecules

Hitendra N. Karade¹  Manisha Sathe¹ 

[1] id="af1-molecules-12-01341">Discovery Center, Process Technology Development Division, Defence R & D Establishment, Jhansi Road, Gwalior 474002 (MP) Ind

关键词: Biginelli reaction;    Dihydropyrimidinones;    silica chloride;    solvent free;   

DOI  :  10.3390/12071341

来源: mdpi

【 摘 要 】

This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.

【 授权许可】

Unknown   
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