Synthesis, Characterization and Antibacterial Activity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid

Molecules

Amjid Iqbal¹  Hamid Latif Siddiqui¹  C. M. Ashraf²  Matloob Ahmad¹ 

[1] Institute of Chemistry, University of the Punjab, Lahore-54590, Pakistan; E-mails:;Department of Chemistry, Forman Christian College (A Chartered University) Lahore-54600, Pakistan; E-mail:

关键词: 2-Formylphenoxyacetic acid;    picoline;    N-phenylhydrazine;    p-toluidine;    o‑bromobenzylamine;    2;    3-dichloroaniline;    p-aminoacetanilide;    imidazole;    thiazole;    antibacterial activity;   

DOI  :  10.3390/12020245

来源: mdpi

【 摘 要 】

A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of ¹H-NMR, ¹³C-NMR, MS and elemental analysis. The compounds were assayed by the disc diffusion method for antibacterial against Staphylococcus aureus and Escherichia coli. Among the compounds tested, 2a, 2b, 2e, 2g and 2h exhibited good antibacterial activity, almost equal to that of Ciprofloxacin used as standard.

【 授权许可】

Unknown   
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