Microwave-Enhanced Sulphated Zirconia and SZ/MCM-41 Catalyzed Regioselective Synthesis of β-Amino Alcohols Under Solvent-Free Conditions

Molecules

Guillermo Negrón-Silva¹  C. Xochitl Hernández-Reyes¹  Deyanira Angeles-Beltrán¹  Leticia Lomas-Romero² 

[1] Departamento de Ciencias Básicas, UAM, Av. San Pablo No 180, C.P. 02200, México D. F., México; E-mails: C. X. Hernández-Reyes:;Departamento de Química, UAM, Av. San Pablo No 180, C.P. 02200, México D. F., México; E-mails: L. Lomas-Romero:

关键词: Sulphated zirconia;    amino alcohols;    microwaves;    regioselective;    oxiranes;   

DOI  :  10.3390/molecules13040977

来源: mdpi

【 摘 要 】

A solvent-free approach for the regioselective synthesis of β-amino alcohols in shorter reaction times and higher yields, compared to conventional heating is described. It involves microwave (MW) exposure of undiluted reactants in the presence of sulphated zirconia (SZ) or sulphated zirconia over MCM-41 (SZM) as catalyst. Both acid materials can be easily recovered and reused.

【 授权许可】

Unknown   
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