Sensors | |
A CMOS Time-Resolved Fluorescence Lifetime Analysis Micro-System | |
Bruce R. Rae3  Keith R. Muir3  Zheng Gong2  Jonathan McKendry2  John M. Girkin1  Erdan Gu2  David Renshaw3  Martin D. Dawson2  | |
[1] Department of Physics, Durham University, South Road, Durham, DH1 3LE, UK; E-Mail:;Institute of Photonics, University of Strathclyde, 106 Rottenrow, Glasgow, G4 0NW, UK; E-Mails:;Institute for Integrated Micro and Nano Systems, The School of Engineering, The University of Edinburgh, The King's Buildings, Mayfield Road, Edinburgh, EH9 3JL, UK; E-Mails: | |
关键词: CMOS; single-photon avalanche diodes; GaN; micro light-emitting diodes (micro-LEDs); fluorescence lifetime; micro-system; | |
DOI : 10.3390/s91109255 | |
来源: mdpi | |
【 摘 要 】
We describe a CMOS-based micro-system for time-resolved fluorescence lifetime analysis. It comprises a 16 × 4 array of single-photon avalanche diodes (SPADs) fabricated in 0.35 μm high-voltage CMOS technology with in-pixel time-gated photon counting circuitry and a second device incorporating an 8 × 8 AlInGaN blue micro-pixellated light-emitting diode (micro-LED) array bump-bonded to an equivalent array of LED drivers realized in a standard low-voltage 0.35 μm CMOS technology, capable of producing excitation pulses with a width of 777 ps (FWHM). This system replaces instrumentation based on lasers, photomultiplier tubes, bulk optics and discrete electronics with a PC-based micro-system. Demonstrator lifetime measurements of colloidal quantum dot and Rhodamine samples are presented.
【 授权许可】
CC BY
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
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