Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents

Molecules

Mosaad S. Mohamed¹  Samir M. Awad¹ 

[1] Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Egypt

关键词: pyrimidine;    6-amino-2-thioxo-1H-pyrimidine-4-one;    antimicrobial;    anti-inflammatory;   

DOI  :  10.3390/molecules15031882

来源: mdpi

【 摘 要 】

A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.