New Constituents from the Rhizomes of Egyptian Iris germanica L.

Molecules

Sabrin R. M. Ibrahim¹  Gamal A. Mohamed¹ 

[1] ¹Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt

关键词: Iris germanica L.;    Iridaceae;    irigenin S;    iriside A;    antimicrobial;    anti-inflammatory;   

DOI  :  10.3390/molecules17032587

来源: mdpi

【 摘 要 】

Chemical investigation of the methanolic extract of the rhizomes of Iris germanica L. (Iridaceae) afforded two new compounds; irigenin S (7) and iriside A (12), together with ten known compounds: stigmasterol (1), a-irone (2), γ-irone (3), 3-hydroxy-5-methoxyacetophenone (4), irilone (5), irisolidone (6), irigenin (8), stigmasterol-3-O-β-D-glucopyranoside (9), irilone 4'-O-b-D-glucopyranoside (10) and iridin (11). Their structures were established by UV, IR, 1D (¹H and ¹³C) and 2D (¹H-¹H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to mass spectroscopic data and comparison with literature data. The methanolic extract was evaluated for its antimicrobial activity. Both the methanolic extract and the isolated flavonoids were tested for their anti-inflammatory activity.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.