Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings

Sensors

Maria Dimaki¹  Patricia Vazquez²  Mark Holm Olsen²  Luigi Sasso²  Romen Rodriguez-Trujillo²  Indumathi Vedarethinam² 

[1] Department of Micro- and Nanotechnology, Technical University of Denmark, DTU Nanotech, Building 345E, Kgs. Lyngby, Denmark;

关键词: 3D electrodes;    fabrication;    neuron differentiation on chip;   

DOI  :  10.3390/s101110339

来源: mdpi

【 摘 要 】

In this paper we discuss the fabrication and characterization of three dimensional (3D) micro- and nanoelectrodes with the goal of using them for extra- and intracellular studies. Two different types of electrodes will be described: high aspect ratio microelectrodes for studying the communication between cells and ultimately for brain slice recordings and small nanoelectrodes for highly localized measurements and ultimately for intracellular studies. Electrical and electrochemical characterization of these electrodes as well as the results of PC12 cell differentiation on chip will be presented and discussed.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland.