Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities

Molecules

Xiao-Dong Li¹  Shuai-Tao Kang¹  Guo-Yu Li¹  Xian Li¹ 

[1] ¹School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China

关键词: phenylpropanoid glycosides;    Rhodiola rosea L.;    acetylcholinesterase/xanthine oxidase inhibitory activity;   

DOI  :  10.3390/molecules16053580

来源: mdpi

【 摘 要 】

In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.