Bioactive Phenylpropanoid Glycosides from Tabebuia avellanedae

Molecules

Maorong Suo¹  Tomihisa Ohta¹  Fumihide Takano¹ 

[1] Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan

关键词: Tabebuia avellanedae Lorentz ex Griseb;    phenylpropanoid glycosides;    antioxidant activity;   

DOI  :  10.3390/molecules18077336

来源: mdpi

【 摘 要 】

Three novel phenylpropanoid glycosides 2, 5, 6 were isolated from water extract of Tabebuia avellanedae, together with three known phenylpropanoid glycosides 1, 3, 4. All compounds were identified on the basis of spectroscopic analysis and chemical methods and, for known compounds, by comparison with published data. All isolated compounds showed strong antioxidant activity in the DPPH assay, and compound 5 give the highest antioxidant activity among all compounds, with an IC₅₀ of 0.12 µM. All compounds exhibited moderate inhibitory effect on cytochrome CYP3A4 enzyme.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.