Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.

Marine Drugs

Shih-Yao Kao¹  Jui-Hsin Su¹  Tsong-Long Hwang⁴  Jyh-Horng Sheu²  Zhi-Hong Wen²  Yang-Chang Wu³ 

[1] Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan; E-Mails:;Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan; E-Mails:;Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan;Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan; E-Mail:

关键词: menelloide;    lindenane;    germacrane;    sesquiterpenoid;    Menella;    elastase;   

DOI  :  10.3390/md9091534

来源: mdpi

【 摘 要 】

Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland