Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

International Journal of Molecular Sciences

Peter A. Ajibade¹ 

关键词: metal complexes;    diisopropylthiourea;    antibacterial;    drug resistance;   

DOI  :  10.3390/ijms12107186

来源: mdpi

【 摘 要 】

Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are consistent with 4-coordinate geometry for the metal(II) complexes and six coordinate octahedral for Fe(III) complex. The complexes were screened for their antibacterial activities against six bacteria: Escherichia coli, Pseudomonas auriginosa, Klebsiella pneumoniae, Bacillus cereus, Staphylococcus aureus and Bacillus pumilus. The complexes showed varied antibacterial activities and their minimum inhibitory concentrations (MICs) were determined.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.