Molecules | |
Two Novel Naphthalene Glucosides and an Anthraquinone Isolated from Rumex dentatus and Their Antiproliferation Activities in Four Cell Lines | |
Hui Zhang1  Zengjun Guo1  Nan Wu1  Wenming Xu1  Ling Han1  Nan Li1  | |
[1] Faculty of Pharmacy, School of Medicine, Xi'an Jiaotong University, No. 76 West Yanta Road, Xi'an 710061, China | |
关键词: naphthalene; glucoside; anthraquinone; Rumex dentatus; antiproliferation; | |
DOI : 10.3390/molecules17010843 | |
来源: mdpi | |
【 摘 要 】
An ethyl acetate extract of the roots of Rumex dentatus L. was investigated. Three compounds were identified by their spectroscopic data as chrysophanol (1), 6-methyl-7-acetyl-1, 8-dihydroxy-3-methoxy naphthalene-1-O-β-D(L)-glucoside (2) and 6-methyl-7-acetyl-1, 8-dihydroxy naphthalene-1-O-β-D(L)-glucoside (3) were found in the plant for the first time. Compounds 2 and 3 are novel compounds. Their antiproliferation activities were tested by the MTT assay in four cell lines (breast cancer MCF-7, gastric cancer 7901, melanoma A375 and oophoroma SKOV-3).
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
Files | Size | Format | View |
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RO202003190046285ZK.pdf | 155KB | download |