Synthesis of a 2,2'-Bipyridyl Functionalized Oligovinylene-Phenylene Using Heck and Horner-Wadsworth-Emmons Reactions and X-ray Crystal Structure of E-(4-(4-Bromostyryl)phenyl)(methyl)sulfane

Molecules

Orsolya Karácsony¹  Jeffrey R. Deschamps¹  Scott A. Trammell¹  Rafaela Nita¹ 

[1] ¹Chemistry Department, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901, USA ²Center for Bio/Molecular Science and Engineering, US Naval Research Laboratory, 4555 Overlook Avenue, SW, Washington, DC 20375, USA ^†Current address: Chemistry Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

关键词: oligovinylphenylene;    HWE reaction;    Heck coupling;   

DOI  :  10.3390/molecules17055724

来源: mdpi

【 摘 要 】

The synthesis of a new 2,2'-bipyridyl functionalized oligovinylenephenylene (OVP-5) containing a methyl protected thiol using Heck coupling and the Horner-Wadsworth-Emmons reaction and is described. A key step involving a diisopropylcarbodiimide promoted dehydration of a stable b-hydroxyphosphonate intermediate was identified. The structure of precursor E-(4-(4-bromostyryl)phenyl)(methyl)sulfane (1) was determined using X-ray crystallography.

【 授权许可】

CC BY   
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