tert-Butyl 1-(Furan-2-yl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-7-carboxylate

Molbank

Rajagopalan Srinivasan¹  Badiadka Narayana¹  Seranthimata Samshuddin¹ 

[1] ¹Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India ²Aurigene Discovery Technologies Limited, Electronics city, Phase-II, Bangalore-560 100, Karnataka, India ³Research Department of Chemistry, P. A College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India

关键词: spirocyclic;    pyrazolone;    ethyl nipecotate;   

DOI  :  10.3390/M757

来源: mdpi

【 摘 要 】

A simple and novel route for synthesis of new spirocyclic compound is developed. The present work involves condensation of ethyl nipecotate with 2-furaldehyde followed by the MnO₂ oxidation to give the β-keto ester which upon reaction with hydrazine hydrate gives the spiro pyrazolone.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.