The Photodegradation of Quercetin: Relation to Oxidation

Molecules

Stefano Dall�qua²  Giorgia Miolo²  Gabbriella Innocenti¹ 

[1]Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy

关键词: quercetin;    photostability;    photodegradation;   

DOI  :  10.3390/molecules17088898

来源: mdpi

【 摘 要 】

The photostability of quercetin in alcoholic solutions was studied. Both UVA and UVB light induced degradation of quercetin, yielding a single product 1 deriving from oxidation and addition of an alcohol molecule to the 2,3 double bond. The same mechanism operated when quercetin was dissolved in alkaline solutions, and again a product 2 due to oxidation and addition of water was characterized. Comparison with quercetin analogs confirmed that, despite the presence of five hydroxy groups in quercetin, those in positions 3, 3′, and 4′ are mainly involved in the antioxidant activity of the compound , as well as in its photolability.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.