Briareolate Esters from the Gorgonian Briareum asbestinum

Marine Drugs

Rian J. Meginley¹  Prasoon Gupta¹  Thomas C. Schulz³  Amanda B. McLean²  Allan J. Robins³ 

[1] Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA;Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, GA 30602, USA;Viacyte Inc., 111 Riverbend Rd, Athens, GA 30602, USA;

关键词: Briareum asbestinum;    octocoral;    briarane;    briareolate ester;    human embryonic stem cell;   

DOI  :  10.3390/md10081662

来源: mdpi

【 摘 要 】

Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2) showed weak growth inhibition activity against human embryonic stem cells (BG02).

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.