Exploratory Spatial Data Analysis of Congenital Malformations (CM) in Israel, 2000–2006

ISPRS International Journal of Geo-Information

Keren Agay-Shay⁴  Yona Amitai²  Chava Peretz¹  Shai Linn⁴  Michael Friger³ 

[1] Department of Epidemiology, Faculty of Medicine, Tel Aviv University, P.O. Box 39040, Ramat Aviv 69978, Israel; E-Mail:;Department of Management, Bar Ilan University, Ramat Gan 52900, Israel; E-Mail:;Department of Epidemiology and Health Services Evaluation, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beersheba 84105, Israel; E-Mail:;Faculty of Social Welfare and Health Sciences, School of Public Health, University of Haifa, Mount Carmel, Haifa 31905, Israel

关键词: birth defects;    congenital malformations;    epidemiology;    spatial clusters/statistics;    LISA;    hot spot;    SaTScan;   

DOI  :  10.3390/ijgi2010237

来源: mdpi

【 摘 要 】

Congenital Malformations (CM) impose a heavy burden on families and society. Identification of spatial patterns of CM is useful for understanding the epidemiology of this public health issue. In Israel, about 1,000,000 births and 25,000 CM cases at 37 groups were geocoded during 2000–2006. These were geo-analyzed using global-Moran’s-I statistics. Eight groups demonstrated geospatial heterogeneity and were further analyzed at both the census tract (Local Indicator of Spatial Association (LISA) and hot spot analyses) and street levels (spatial scan statistics with two population threshold sizes). The positional definition of results is further discussed in relevance to possible exposure to teratogenic sources in the region. Limitations of data and methods used are presented as well.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.