Neural Repair and Neuroprotection with Stem Cells in Ischemic Stroke

Brain Sciences

Laura L. Stone¹  Andy Grande² 

[1] Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA; E-Mail:;Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA; E-Mail:

关键词: ischemia;    ischemic brain injury;    neuroprotection;    stem cells;    stroke;   

DOI  :  10.3390/brainsci3020599

来源: mdpi

【 摘 要 】

Stem cells have been touted as a potential source of cells for repair in regenerative medicine. When transplanted into the central nervous system, stem cells have been shown to differentiate into neurons and glia. Recent studies, however, have also revealed neuroprotective properties of stem cells. These studies suggest that various types of stem cells are able to protect against the loss of neurons in conditions of ischemic brain injury. In this article, we discuss the use of stem cells for ischemic stroke and the parameters under which neuroprotection can occur in the translation of stem cell therapy to the clinical setting.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.