A Preliminary Study of the Effect of DBD Plasma and Osmolytes on T98G Brain Cancer and HEK Non-Malignant Cells

Molecules

Nagendra Kumar Kaushik¹  Pankaj Attri²  Neha Kaushik² 

[1] Plasma Bioscience Research Center, Kwangwoon University, Seoul 139701, Korea;

关键词: osmolytes;    plasma;    brain cancer cells;    non-malignant cells;   

DOI  :  10.3390/molecules18054917

来源: mdpi

【 摘 要 】

Non-thermal plasmas are emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study, we described the effect of 4 min dielectric barrier discharge (DBD) plasma on both T98G cancer and HEK normal cell lines in the presence of different concentrations of osmolytes. This treatment strategy shows a specific inhibitory effect of a 240 s plasma exposure in the presence of osmolytes against T98G brain cancer cells only, but not on HEK normal cells. Based on these interesting properties of osmolytes, a non-thermal plasma appears to be a potential anticancer treatment strategy for different kinds of cancers in the presence of osmolytes.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.