Marine Drugs | |
Epigonal Conditioned Media from Bonnethead Shark, |
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Catherine J. Walsh1  Carl A. Luer2  Jennifer E. Yordy1  Theresa Cantu1  Jodi Miedema1  Stephanie R. Leggett1  Brittany Leigh1  Philip Adams1  Marissa Ciesla1  Courtney Bennett1  | |
[1] Marine Immunology Program, Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA;Marine Biomedical Program, Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA; E-Mails: | |
关键词: epigonal organ; bonnethead shark; Jurkat; apoptosis; tumor cell line; | |
DOI : 10.3390/md11093224 | |
来源: mdpi | |
【 摘 要 】
Representatives of Subclass Elasmobranchii are cartilaginous fish whose members include sharks, skates, and rays. Because of their unique phylogenetic position of being the most primitive group of vertebrates to possess all the components necessary for an adaptive immune system, the immune regulatory compounds they possess may represent the earliest evolutionary forms of novel compounds with the potential for innovative therapeutic applications. Conditioned medium, generated from short term culture of cells from the epigonal organ of bonnethead sharks (
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190033744ZK.pdf | 2339KB | download |