New Diterpenoids from Soft Coral Sarcophyton ehrenbergi

Marine Drugs

Shang-Kwei Wang²  Mu-Keng Hsieh¹ 

[1] Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan;Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan; E-Mail:

关键词: Sarcophyton ehrenbergi;    diterpenoids;    cytotoxicity;    anti-HCMV;   

DOI  :  10.3390/md11114318

来源: mdpi

【 摘 要 】

Continuing chemical investigation on the acetone extracts of the soft coral Sarcophyton ehrenbergi collected off the coast of San-hsian-tai, Taitong County, Taiwan led to the isolation of two new diterpenoids, ehrenbergol C and acetyl ehrenberoxide B (1 and 2). The structures of these isolated metabolites were elucidated through extensive spectroscopic analyses. Moreover, in vitro tests show that compounds 1 and 2 displayed antiviral activity towards human cytomegalovirus, with EC₅₀ of 20 and 8.0 µg/mL, respectively.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.