Long-Term Consumption of Oats in Adult Celiac Disease Patients

Nutrients

Katri Kaukinen¹  Pekka Collin¹  Heini Huhtala² 

[1] Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere FIN-33521, Finland; E-Mail:;School of Health Sciences, University of Tampere, Tampere FIN-33014, Finland; E-Mail:

关键词: celiac disease;    gluten-free diet;    morphology;    oats;    questionnaire;    small-bowel;   

DOI  :  10.3390/nu5114380

来源: mdpi

【 摘 要 】

Many celiac disease patients tolerate oats, but limited data are available on its long-term consumption. This was evaluated in the present study, focusing on small-bowel mucosal histology and gastrointestinal symptoms in celiac adults maintaining a strict gluten-free diet with or without oats. Altogether 106 long-term treated celiac adults were enrolled for this cross-sectional follow-up study. Daily consumption of oats and fiber was assessed, and small-bowel mucosal morphology and densities of CD3+, αβ+ and γσ+ intraepithelial lymphocytes determined. Gastrointestinal symptoms were assessed by a validated Gastrointestinal Symptom Rating Scale questionnaire. Seventy (66%) out of the 106 treated celiac disease patients had consumed a median of 20 g of oats (range 1–100 g) per day for up to eight years; all consumed oat products bought from general stores. Daily intake and long-term consumption of oats did not result in small-bowel mucosal villous damage, inflammation, or gastrointestinal symptoms. Oat-consumers had a significantly higher daily intake of fiber than those who did not use oats. Two thirds of celiac disease patients preferred to use oats in their daily diet. Even long-term ingestion of oats had no harmful effects.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.