The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis

Nutrients

Katri Kaukinen¹  Eriika Mansikka¹  Laura Kivelä¹  Pilvi Laurikka¹  Teea Salmi²  Kaisa Hervonen²  Timo Reunala²  Anna Alakoski²  Kalle Kurppa³  Heini Huhtala⁴ 

[1] Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland;Department of Dermatology, Tampere University Hospital, 33521 Tampere, Finland;Department of Paediatrics, Tampere University Hospital, 33521 Tampere, Finland;Faculty of Social Sciences, Tampere University, 33014 Tampere, Finland;

关键词: dermatitis herpetiformis;    coeliac disease;    gluten-free diet;    oats;    quality of life;    complications;   

DOI  :  10.3390/nu12041060

来源: DOAJ

【 摘 要 】

The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients.

【 授权许可】

Unknown