期刊论文详细信息
International Journal of Molecular Sciences
Single Nucleotide Polymorphisms in Growth Hormone Gene and Their Association with Growth Traits in Siniperca chuatsi (Basilewsky)
Changxu Tian2  Min Yang2  Liyuan Lv2  Yongchao Yuan1  Xufang Liang1  Wenjie Guo2  Yi Song2 
[1] Key Lab of Freshwater Animal Breeding, Ministry of Agriculture, Freshwater Aquaculture Collaborative Innovation Center of Hubei Province, College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China;
关键词: Siniperca chuatsi;    GH gene;    SNP;    growth traits;   
DOI  :  10.3390/ijms15047029
来源: mdpi
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【 摘 要 】

Growth hormone (GH) has been considered as a candidate gene for growth traits in fish. In this study, polymorphisms of the GH gene were evaluated for associations with growth traits in 282 Siniperca chuatsi individuals. Using directly sequencing, four single nucleotide polymorphisms (SNPs) were identified in GH gene, with two mutations in intron 4 (g.4940A>C, g.4948A>T), one mutation in exon 5 (g.5045T>C) and one in intron 5 (g.5234T>G). Notably, three of them were significantly associated with growth performance, particularly for g.4940A>C which was highly correlated with all the four growth traits. In conclusion, our results demonstrated that these SNPs in GH gene could influence growth performance of S.chuatsi and could be used for marker-assisted selection (MAS) in this species.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland

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