SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases

International Journal of Molecular Sciences

Barbara Palumbo¹  Tommaso Buresta¹  Susanna Nuvoli²  Angela Spanu²  Orazio Schillaci³  Mario Luca Fravolini⁴ 

[1] Section of Nuclear Medicine and Health Physics, Department of Surgical and Biomedical Sciences, University of Perugia, Perugia 06100, Italy; E-Mail:;Section of Nuclear Medicine, Department of Clinical and Experimental Medicine, University of Sassari, Sassari 07100, Italy; E-Mails:;Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma 00133, Italy; E-Mail:;Department of Engineering, University of Perugia, Perugia 06100, Italy; E-Mail:

关键词: brain metastases;    molecular imaging;    PET;    SPECT;    MRI;    fusion imaging;   

DOI  :  10.3390/ijms15069878

来源: mdpi

【 摘 要 】

Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.