Cervical SPECT Camera for Parathyroid Imaging

关键词: CZT;    parathyroid;    molecular imaging;    gamma detector;    direct detection;    pinhole imaging;   

DOI  :  10.2172/1049698
RP-ID  :  DOE/ER/83962-1 Final Report
PID  :  OSTI ID: 1049698

美国|英语

来源: SciTech Connect

【 摘 要 】

Primary hyperparathyroidism characterized by one or more enlarged parathyroid glands has become one of the most common endocrine diseases in the world affecting about 1 per 1000 in the United States. Standard treatment is highly invasive exploratory neck surgery called Parathyroidectomy. The surgery has a notable mortality rate because of the close proximity to vital structures. The move to minimally invasive parathyroidectomy is hampered by the lack of high resolution pre-surgical imaging techniques that can accurately localize the parathyroid with respect to surrounding structures. We propose to develop a dedicated ultra-high resolution (~ 1 mm) and high sensitivity (10x conventional camera) cervical scintigraphic imaging device. It will be based on a multiple pinhole-camera SPECT system comprising a novel solid state CZT detector that offers the required performance. The overall system will be configured to fit around the neck and comfortably image a patient.