Chemoresistive Gas Sensors for the Detection of Colorectal Cancer Biomarkers

Sensors

Cesare Malagù¹  Barbara Fabbri¹  Sandro Gherardi¹  Alessio Giberti¹  Vincenzo Guidi¹  Nicolò Landini¹ 

[1] Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy; E-Mails:

关键词: gas;    sensors;    nanotechnology;    semiconductors;    metal oxides;    colorectal cancer;    VOC;    1-iodo-nonane;   

DOI  :  10.3390/s141018982

来源: mdpi

【 摘 要 】

Numerous medical studies show that tumor growth is accompanied by protein changes that may lead to the peroxidation of the cell membrane with consequent emission of volatile organic compounds (VOCs) by breath or intestinal gases that should be seen as biomarkers for colorectal cancer (CRC). The analysis of VOCs represents a non-invasive and potentially inexpensive preliminary screening technique. An array of chemoresistive gas sensors based on screen-printed metal oxide semiconducting films has been selected to discriminate gases of oncological interest, e.g., 1-iodononane and benzene, widely assumed to be biomarkers of colorectal cancer, from those of interference in the gut, such as methane and nitric oxide.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.