Molecules | |
Characterization of Ambrette Seed Oil and Its Mode of Action in Bacteria | |
Selvaraj Arokiyaraj3  Seong Ho Choi7  Yoonseok Lee3  Rajaraman Bharanidharan1  Villianur Ibrahim Hairul-Islam6  Badathala Vijayakumar2  Young Kyoon Oh5  Vannam Dinesh-Kumar4  Savariar Vincent4  Kyoung Hoon Kim3  | |
[1] Department of Biotechnology, Vel Tech High Tech Dr.Rangarajan Dr.Sakunthala Engineering College (Anna University), Chennai 600062, India; E-Mail:;Department of Chemistry, Vel Tech High Tech Dr.Rangarajan Dr.Sakunthala Engineering College (Anna University), Chennai 600062, India; E-Mail:;Institute of Green Bio Science & Technology, Seoul National University, Pyeongchang-daero 232916, Korea; E-Mails:;Centre for Environment Research and Development, Loyola College, Chennai 600034, India; E-Mails:;Department of Animal Nutrition and Physiology, National Institute of Animal Science, Rural Development Administration, Suwon 441706, Korea; E-Mail:;Pondicherry Centre for Biological Sciences, Pondicherry 605005, India; E-Mail:;Department of Animal Science, Chungbuk National University, Chunbuk 361763, Korea; E-Mail: | |
关键词: ambrette seed oil; antibacterial activity; chemical composition; docking; DHFR; | |
DOI : 10.3390/molecules20010384 | |
来源: mdpi | |
【 摘 要 】
In the present study, chemical composition and the antibacterial mechanism of ambrette seed oil are investigated. Chemical composition of the oil was analysed by gas chromatography-mass spectrometry (GC-MS). Thirty-five compounds were identified and the major compounds were found to be farnesol acetate (51.45%) and ambrettolide (12.96%). The antibacterial activity was performed by well diffusion assay and the mechanisms were studied by measuring the alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and protein leakage assays. The antibacterial effect of the ambrette seed oil showed inhibitory effect against
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
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