Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy

Micromachines

Casper Hyttel Clausen²  Gustav Erik Skands¹  Christian Vinther Bertelsen²  Winnie Edith Svendsen² 

[1] SBT Aqua ApS, Diplomvej 381, 2800 Kgs. Lyngby, Denmark; E-Mail:;Department of Micro- and Nanotechnology, Technical University of Denmark, Oersteds Plads 345 East, DK 2800 Kgs. Lyngby, Denmark; E-Mails:

关键词: electrical impedance spectroscopy;    sensitivity;    improved design;    impedance flow cytometry;   

DOI  :  10.3390/mi6010110

来源: mdpi

【 摘 要 】

This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 μm beads from 1 μm as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.