Chemical Composition and Biological Activities of the Essential Oil of Skimmia laureola Leaves

Molecules

rib-type="author">Barkatullah1Barkatullah²  Muhammad Ibrar²  Naveed Muhammad³  Vincenzo De Feo¹ 

[1] Department of Pharmacy, University of Salerno, Fisciano 84084, Italy;Department of Botany, University of Peshawar, Peshawar 25000, Pakistan; E-Mails:;Department of Pharmacy, Abdul Wali Khan University, Mardan 23200, Pakistan; E-Mail:

关键词: Skimmia laureola;    antispasmodic activity;    antibacterial activity;    antifungal activity;    phytotoxic activity;    cytotoxic activity;   

DOI  :  10.3390/molecules20034735

来源: mdpi

【 摘 要 】

The composition of the essential oil from leaves of Skimmia laureola was determined by GC and GC-MS. Twenty-eight components were identified, accounting for 93.9% of the total oil. The oil is mainly composed of monoterpenes (93.5%), of which monoterpene hydrocarbons and oxygenated monoterpenes represent 11.0% and 82.5%, respectively. Sesquiterpenes constitute only 0.3% of the total oil. Linalyl acetate is the main component (50.5%), with linalool (13.1%), geranyl acetate (8.5%) and cis-p-menth-2-en-1-ol (6.2%) as other principal constituents. The essential oil showed a significant antispasmodic activity, in a dose range of 0.03–10 mg/mL. The essential oil also possesses antibacterial and antifungal activities against some pathogenic strains. The phytotoxic and cytotoxic activities were also assessed.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.