The Activities and Impact of State Programs to Address Hereditary Breast and Ovarian Cancer, 2011–2014

Healthcare

Katrina F. Trivers²  Juan L. Rodriguez²  Summer L. Cox⁴  Barbara E. Crane³  Debra Duquette¹ 

[1] Michigan Department of Health and Human Services, Lansing, MI 48909, USA; E-Mail:;Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA; E-Mail:;Georgia Department of Public Health, Atlanta, GA 30303-3142, USA; E-Mail:;Oregon Health Authority, Portland, OR 97232, USA; E-Mail:

关键词: genomics;    genetic services;    implementation;    state health departments;    BRCA;    breast cancer;    ovarian cancer;    hereditary breast;    ovarian cancer;   

DOI  :  10.3390/healthcare3040948

来源: mdpi

【 摘 要 】

In 2011, the Division of Cancer Prevention and Control (DCPC), at the United States Centers for Disease Control and Prevention (CDC), released a three-year funding opportunity announcement (FOA) for a competitive, non-research cooperative agreement. The agreement enhanced the capacities of state health departments to promote the application of best practices for evidence-based breast cancer genomics through education, surveillance, and policy activities. The FOA required that applicants focus on activities related to hereditary breast and ovarian cancer (HBOC). The DCPC funded three states: Georgia, Michigan, and Oregon. Georgia was a first-time recipient of cancer genomics funding, whereas Michigan and Oregon had long standing activities in cancer genomics and had received CDC funding in the past. By the end of the funding period, each state had well-functioning and impactful state-based programs in breast cancer genomics. This article highlights the impact of a few key state activities by using CDC’s Science Impact Framework. There were challenges to implementing public health genomics programs, including the need to develop relevant partnerships, the highly technical nature of the subject matter, a lack of genetic services in certain areas, and the difficulty in funding genetic services. Georgia, Michigan, and Oregon have served as models for others interested in initiating or expanding cancer genomics programs, and they helped to determine what works well for promoting and integrating public health genomics into existing systems.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.