Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

Metabolites

Martin C. Lai²  Ethan I. Lan¹ 

[1] Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 300, Taiwan;Undergraduate Honors Program of Nano Science and Engineering, National Chiao Tung University, Hsinchu 300, Taiwan; E-Mail:

关键词: metabolic engineering;    cyanobacteria;   

DOI  :  10.3390/metabo5040636

来源: mdpi

【 摘 要 】

Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability. Cyanobacteria naturally grow on light and carbon dioxide, bypassing the need of fermentable plant biomass and arable land. By tapping into the central metabolism and rerouting carbon flux towards desirable compound production, cyanobacteria are engineered to directly convert CO₂ into various chemicals. This review discusses the diversity of bioproducts synthesized by engineered cyanobacteria, the metabolic pathways used, and the current engineering strategies used for increasing their titers.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.