Synthesis and Sensing Applications of Fluorescent 3-Cinnamoyl Coumarins

Sensors

Preeti Yadav²  Hardeep Singh Gill¹  Karam Chand²  Lian Li¹  Jayant Kumar¹  Sunil K. Sharma² 

[1] Center for Advanced Materials, University of Massachusetts Lowell, Lowell, MA 01854, USA;Department of Chemistry, University of Delhi, Delhi 110007, India;

关键词: 3-(4-diethylaminocinnamoyl) coumarins;    fluorescence;    DCP;    nerve gas sensors;    two-photon fluorescence;   

DOI  :  10.3390/s151229902

来源: mdpi

【 摘 要 】

We have synthesized two novel fluorescent 3-(4-diethylaminocinnamoyl) coumarins that exhibit fluorescence quenching upon exposure to a nerve agent simulant, diethylchlorophosphate (DCP), providing a basis for rapid and sensitive DCP chemosensing. Furthermore, these coumarin derivatives display two-photon fluorescence upon illumination with near-infrared laser pulses and their two-photon (TP) absorption cross-section was evaluated. The potential for TP bio-imaging of these compounds was investigated by their cellular uptake in HeLa cells by TP confocal microscopy.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.