Fatty Acid Profile and Biological Activities of Linseed and Rapeseed Oils

Molecules

Anna Lewinska⁴  Jacek Zebrowski³  Magdalena Duda²  Anna Gorka⁵  Maciej Wnuk¹ 

[1]Department of Genetics, University of Rzeszow, Rejtana 16C, 35-959 Rzeszow, PolandDepartment of Botany, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland

[2]Department of Plant Physiology, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland

[3]Department of Biochemistry and Cell Biology, University of Rzeszow, Zelwerowicza 4, 35-601 Rzeszow, Poland

[4]Department of Animal Physiology and Reproduction, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland

关键词: linseed oil;    rapeseed oil;    FTIR spectroscopy;    gas chromatography;    scratch wound healing assay;    fibroblasts;   

DOI  :  10.3390/molecules201219887

来源: mdpi

【 摘 要 】

It has been postulated that fatty acids found in edible oils may exert beneficial health effects by the modulation of signaling pathways regulating cell differentiation and proliferation, especially in the treatment of cardiovascular diseases. In the present study, the biological effects of selected edible oils—linseed (LO) and rapeseed (RO) oils—were tested in vitro on fibroblast cells. The fatty acid profile of the oils was determined using gas chromatography and FTIR spectroscopy. LO was found to be rich in α-linolenic acid (ALA), whereas oleic acid was the most abundant species in RO. Fatty acids were taken up by the cells and promoted cell proliferation. No oxidative stress-mediated cytotoxic or genotoxic effects were observed after oil stimulation. Oils ameliorated the process of wound healing as judged by improved migration of fibroblasts to the wounding area. As ALA-rich LO exhibited the most potent wound healing activity, ALA may be considered a candidate for promoting the observed effect.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.