Value of Core Needle Biopsy as the First Diagnostic Procedure in the Palpable Breast Masses.

lranian journal of Clinical Infectious Diseases

A Aminian¹  R Mirsharifi²  AP Meysamie³  A Alibakhshi¹  F Karimian¹  E Hashemi⁴ 

[1] Assistant Professor, Department of General Surgery, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.;Associate Professor, Department of General Surgery, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.;Assistant Professor, Department of General Surgery, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. General Surgeon, Iranian Center for Breast Cancer, Tehran, Iran Assistant Professor of Community Medicine, Tehran University of Medical Sciences, Tehran, Iran;Assistant Professor, Department of General Surgery, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. General Surgeon, Iranian Center for Breast Cancer, Tehran, Iran

关键词: Breast mass;    breast cancer;    malignancy;    biopsy;    core needle biopsy;   

DOI  :  10.17795/semj20854

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Background:Breastcoreneedlebiopsy(CNB)providesenoughtissueforhistopathologicdiagnosisandisconsideredareliablemethodforestablishingpreoperativetissuediagnosis.ThepurposeofthisstudyistoevaluateCNBasthefirstdiagnosticstepinsteadofexcisionalbiopsyinpalpablebreastmasses.MaterialsandMethods:Inthisprospectivestudy,patientswithpalpablebreastmasswhounderwentCNBwereenrolled.Basedonpathologyreport,patientswithmalignantlesionsrevealedbyCNBwereimmediatelycandidateforsurgeryandthosewhohadbenignlesionswerefollowedupto3years.Results:112femaleswithpalpablebreastmasswereenrolledinthestudy.In103(91.9%)ofcasesfirstattemptCNBprovidedadequatesampletissue.CNBdetectedmalignantlesioninseventyeight(69.6%)patients.All(100%)malignantCNBreportswereconfirmedatsurgeryspecimenpathology.In34(30.4%)patientsCNBrevealedbenignlesion.Attheendof3yearsfollowupperiod,25(73%)ofthesepatientsunderwentopenbiopsyleadingtothedetectionof1(3%)malignanttumor.Overall,accordingtothegoldstandarddefinedaspositivesurgicalbiopsyorpositivefollow-up,sensitivityofCNBwascalculatedas98.7%(95%CI,94.1-100%)anditsaccuracywas99.1%(95%CI,97.4-100%).ThespecificityoftheCNBprocedurewas100%.Conclusion:ThesefindingssuggestthatthemalignancydetectionpowerprovidedbyCNBmaybeweighedequaltothatofopenbiopsy.Therefore,weproposeCNBasthefirstchoiceindiagnosticevaluationofpalpablebreastmassespeciallyforthoseinaccessiblesitesandinexperiencedhands.

【 授权许可】

Unknown