Developmental Biology | |
Anteroposterior Patterning in Adult Abdominal Segments of Drosophila | |
Artyom Kopp1  Ian Duncan1  | |
[1] Department of Biology, Washington University, St. Louis, Missouri, 63130 | |
关键词: hedgehog; engrailed; optomotor-blind; segment polarity; homeotic genes; bithorax complex; abdominal histoblasts; | |
DOI : 10.1006/dbio.2001.0529 | |
学科分类:生物科学(综合) | |
来源: Academic Press | |
【 摘 要 】
ThecuticleoftheadultabdomenofDrosophilaisproducedbynestsofimaginalhistoblasts,whichproliferateandmigrateduringmetamorphosistoreplacethepolyploidlarvalepidermalcells.Inthisreport,wepresentadetaileddescriptionoftheexpressionoffourkeypatterninggenes,engrailed(en),hedgehog(hh),patched(ptc),andoptomotor-blind(omb),inabdominalhistoblastsduringthefirst42hafterpupariation,aperiodinwhichtheadultpatternisestablished.Inaddition,wedescribetheexpressionofthehomeoticgenesUltrabithorax,abdominal-A,andAbdominal-B,whichspecifythefatesofadultabdominalsegments.Ourresultsindicatethatabdominalsegmentsdevelopinisolationfromoneanotherduringearlypupalstages,andthatsomepatterningeventsareindependentofhh,wingless,anddecapentaplegicsignaling.WeshowthatpatternandpolarityinalargeanteriorportionofthesegmentarespecifiedwithoutinputfromHh,andpresentevidencethatabdominaltergitespossessanunderlyingsymmetricpatternuponwhichpatterningbyHhissuperimposed.Thesignalsresponsibleforthisunderlyingsymmetryremaintobeidentified.
【 授权许可】
Unknown
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