Homologues of the engrailed gene from five molluscan classes

FEBS Letters

Kostriken, R.⁴  Wray, C.G.¹  Baker, R.²  DeSalle, R.²  Jacobs, D.K.¹  Vogler, A.P.³ 

[1] Department of Biology, University of California, 621 Circle Drive South, Los Angeles, CA 90095-1606, USA;American Museum of Natural History, Central Park West at 79th Street, New York, NY 10024, USA;Department of Entomology, The Natural History Museum, Cromwell Road, London, SW7 5BD, UK;Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY 10595, USA

关键词: engrailed;    Mollusc;    Homeodomain;    Homology;    Segmentation;    Evolution;   

DOI  :  10.1016/0014-5793(95)00372-G

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We used the polymerase chain reaction (PCR) to amplify, clone, and sequence 10 engrailed homeodomains from 8 species in the five major molluscan classes, including the serially organized chiton (Polyplacophora) lineage. The Drosophila melanogaster gene engrailed (en) is one of several genes involved in embyonic segment polarity determination. Studies of engrailed sequence and expression in molluscs are of interest due to questions regarding the evolution and homology of segmentation in these taxa. Nucleotide and deduced amino acid sequence comparisons reflect evolutionary conservation within helices of the en homeodomain and ancient divergences in the region 3′ to the homeodomain.

【 授权许可】

Unknown