Study of vitamin D3 level in patients with diabetes mellitus

International Journal of Biomedical and Advance Research

Vishwal Indravadan Patel¹  Haridas Neelakandan Nilayangode¹  Kaushik Salubhai Chaudhari¹  Mayur Goradhanbhai Makadia¹  Aashna Darshanbhai Shah¹  Kinjal Prahaladbhai Patel¹ 

关键词: Vitamin D3;    Glycated Hemoglobin (HbA1c);    Diabetes Mellitus;   

DOI  :  10.7439/ijbar.v7i7.3420

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Introduction:Glycated hemoglobin (HbA1c) is primarily measured to identify glycemic control in diabetic patients. According to The American Diabetes Association (ADA), and World Health Organization (WHO), HbA1c concentrations 6.5% or more is diagnostic of diabetes. Vitamin D 3deficiency has high prevalence all over the India. It has been proposed that mild to moderate vitamin D 3deficiency is a risk factor for type 2 diabetes and higher plasma vitamin D 3is related to a lower risk for the development of diabetes mellitus in high-risk patients. Aim and Objectives:The aim was to study the levels of vitamin D 3and relationship between the levels of vitamin D 3and HbA1c in diabetic patients. Material and Method:HbA1c and vitamin D 3were measured in 100 diabetic patients, and another 100 age and sex matched normal healthy individuals. HbA1c was measured by Immunoturbidimetry and vitamin D 3was measured by Electrochemiluminescence. Results:The mean vitamin D 3level in diabetic patients (27.19 ? 6.03 nmol/L) was significantly lower than healthy individuals (61.13 ? 10.85 nmol/L) (P <0.001). There was an inverse correlation between the levels of vitamin D 3and HbA1c (Pearson?? correlation coefficient, r = -0.63, P <0.001). Conclusion:Vitamin D3 levels are deficient in diabetic patients, and there is an inverse correlation between the levels of vitamin D3 and HbA1c. So, the level of vitamin D3 is inversely associated with glycemic control in diabetic patients. Therefore, vitamin D3 supplementation may be helpful in the treatment of Diabetes Mellitus.

【 授权许可】

CC BY