Preliminary report on the efficacy of a chamomile (Matricaria chamomilla) and linseed (Linum usitatissimum) based saliva substitute formulated for the relief of xerostomia in the elderly

Revista clínica de periodoncia, implantología y rehabilitación oral

Manríquez Urbina, José¹  Aitken Saavedra, Juan Pablo¹  Rojas Alcayaga, Gonzalo¹  Morales Bozo, Irene¹  Lefimil Puente, Claudia¹  Centro de Referencia de Salud Peñalolén Cordillera Oriente, Santiago, Chile¹  Ortega Pinto, Ana¹  Lozano Moraga, Carla¹  Urzúa Orellana, Blanca¹  Salinas Flores, Juana Olga¹  Universidad de Chile, Santiago, Chile¹ 

关键词: Xerostomia;    Substitute;    Saliva;    Chamomile;    Linseed;   

DOI  :  10.1016/j.piro.2015.01.001

来源: Sociedad de Periodoncia de Chile

【 摘 要 】

Introduction Xerostomia is a common chronic health condition that affects a great number of elderly people. Palliative treatment, such as salivary substitutes should be used, but these products are not accessible in the Chilean market. Objectives To evaluate the efficacy of a new Chamomile and linseed based saliva substitute in the reduction of xerostomía-associated symptomatology in elderly people. Methodology Forty elderly subjects presenting with xerostomia of various origins were selected. Chamomile and linseed based saliva substitute and a carboxymethylcellulose based conventional artificial saliva were tested using a double-blind, randomized, cross-over clinical trial with an intervining wash out period. Results All (100%) of subjects had a sensation of dry mouth, and 58.8% mentioned a sensation of thick saliva, 52.9% needed to drink liquids to swallow, and with a sensation of swallowing difficulty. Burning tongue sensation was recorded in 23.5% of the patients. The most frequent pathologies in the sample were arterial hypertension and arthritis. Results of the clinical tests showed that Chamomile and linseed based saliva substitute significantly relieves the sensation of dry mouth and the sensation of thick saliva (Wilcoxon test P < .05). Conclusion New chamomile and linseed based saliva substitute was effective in relieving xerostomia symptoms in elderly people, and could improve the quality of life of population affected by this condition.

【 授权许可】

Unknown