An evaluation of the effect of acupuncture on salivary pH and the Xerostomia Inventory score innasopharyngeal carcinoma patients with chemoradiation-induced xerostomia

1st Physics and Technologies in Medicine and Dentistry Symposium

物理学;医药卫生

Mihardja, H.^1 ; Susworo, R.^2 ; Srilestari, A.^1 ; Umri, H.^1

Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia^1

Department of Radiotherapy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia^2

关键词: Acupuncture therapy;    Carcinoma patients;    Chemo radiations;    Indonesia;    Nasopharyngeal carcinoma;    Radiation-induced;    Side effect;    Xerostomia;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/884/1/012127/pdf
DOI  :  10.1088/1742-6596/884/1/012127

学科分类：卫生学

来源: IOP

【 摘 要 】

Radiation-induced xerostomia is a distressing side-effect of radiation for nasopharyngeal carcinoma (NPC) treatment, commonly occurring in almost 100% of patients who undergo this procedure. It has been proposed that acupuncture can be used to treat radiation-induced xerostomia. To the best of our knowledge, the current study constitutes the first acupuncture research that has been conducted in Indonesia on xerostomia following chemo-irradiation in NPC patients. Twenty-five patients with xerostomia due tochemo-irradiation for NPC were divided randomly into three groups of auriculopuncture (group A), body acupuncture (group B), and combination acupuncture (group C). The subjects were evaluated according to Xerostomia Inventory scores before and after six and 12 acupuncture treatments. Salivary pH was determined before and after the 12th acupuncture treatment using a saliva check buffer kit. The success rate of acupuncture therapy in group A was 71-100%, 68-89% ingroup B, and 89-100% in group C (p > 0.050). The mean salivary pH increased after therapy from 6.18±0.60 to 6.83±4.48 in group A, from 6.16±0.54 to 6.67±2.26 in group B, and from 6.00±0.40 to 6.60±2.23 in group C (p > 0.050). After the 12th acupuncture therapy session, the mean Xerostomia Inventory score decreased from 35.70±5.14 prior to acupuncture therapy to 22.89±16.15 after it in group A, with corresponding decreases of 34.70±7.77 to 20.89±10.06 in group B, and of 36.70±5.25 to 21.44±8.97 in group C (p > 0.050). Auriculopuncture, body acupuncture, and combination acupuncture had the same effect of increasing salivary pH and decreasing the Xerostomia Inventory score in patients with xerostomia following chemo irradiation for NPC.