Quinine: 470 years of history, controversy and science development

Química Nova

Szczerbowski, Daiane¹  Universidade Federal do Paraná, Curitiba, Brasil¹  Oliveira, Alfredo Ricardo Marques de¹ 

关键词: quinine;    chemical industry;    Cinchona alkaloids.;   

DOI  :  10.1590/S0100-40422009000700048

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

After 470 years, a history of development, international seed smuggling and scientific development that caused deep changes in our society, has reached an end. In 1638, the countess of Chinchón contracted a disease while in the Amazon rain forest and was healed by a potion used by the native inhabitants. In 1856, William H. Perkin while attempting to obtain synthetic quinine, discovered the mauveína, a molecule that changed the world. The synthesis of quinine was also the subject of a bitter controversy among two excellent scientists of the 20th century. During centuries, quinine was the only hope against malaria disease and its exploration almost extinguished the Cinchona tree.

【 授权许可】

Unknown