Quinine: 470 years of history, controversy and science development

Quimica nova

Szczerbowski, Daiane¹  Oliveira, Alfredo Ricardo Marques de¹ 

[1] Universidade Federal do Paraná, Curitiba, Brasil

关键词: quinine;    chemical industry;    Cinchona alkaloids.;   

DOI  :  10.1590/S0100-40422009000700048

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

After 470 years,a history of development, international seed smuggling and scientific developmentthat caused deep changes in our society, has reached an end. In 1638, the countessof Chinchón contracted a disease while in the Amazon rain forest andwas healed by a potion used by the native inhabitants. In 1856, William H. Perkinwhile attempting to obtain synthetic quinine, discovered the mauveína,a molecule that changed the world. The synthesis of quinine was also the subjectof a bitter controversy among two excellent scientists of the 20thcentury. During centuries, quinine was the only hope against malaria diseaseand its exploration almost extinguished the Cinchona tree.

【 授权许可】

CC BY