期刊论文详细信息
Química Nova
Antibacterial activity of the phloroglucinols and hexanic extract from Hypericum brasiliense Choysi
Rito, Priscila da Nóbrega1  Teixeira, Lenise Arneiro1  Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil1  Universidade Federal Fluminense, Niterói, Brasil1  Kuster, Ricardo Machado1  França, Hildegardo Seibert1  Oliveira, Adriana Passos de1  Rocha, Leandro1 
关键词: Hypericum brasiliense;    antibacterial activity;    phloroglucinol.;   
DOI  :  10.1590/S0100-40422009000500004
学科分类:化学(综合)
来源: Sociedade Brasileira de Quimica
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【 摘 要 】

Three phloroglucinols were obtained from Hypericum brasiliense: japonicine A (1), isouliginosin B (2) and uliginosin B (3). Bioautography and disk diffusion methods were used to determine antibacterial activity of the hexanic extract. Strains of the Coagulase Negative Staphylococcus and American Methicillin Resistant Staphylococcus aureus clones showed a growth inhibition zone ranging from 10 to 12 mm and 7 to 15 mm, respectively. Minimal inhibitory concentration (MIC) values were used to measure antistaphylococcal activity for all phloroglucinols. Isouliginosin B and uliginosin B presented MIC values of 1.5 and 3.0 µg/mL, respectively, while japonicine A displayed MIC value of 50.0 µg/mL.

【 授权许可】

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